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KMID : 1024520120210070875
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Journal of the Environmental Sciences
2012 Volume.21 No. 7 p.875 ~ p.881
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Anti-hyperlipidemic Effects of Cordyceps militaris Hot-Water Extract
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Kim Han-Soo
Kim Min-A
Jang Seong-Ho
Lee Won-Ki
Ryu Jae-Young
Lee Chun-Sik
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Abstract
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This study was performed to observe the effects of the feeding physiological activity substance in Cordyceps militaris hot-water extract intake on the improvement of lipid components and metabolic enzyme activities in the serum of dietary hyperlipidemic rats (SD strain, male) fed the experimental diets for 5 weeks. The concentrations of cholesterol (total cholesterol, ${\beta}$ 수식 이미지-lipoprotein, LDL-cholesterol, free cholesterol and cholesteryl ester), atherosclerotic index, triglyceride (TG), phospholipid (PL) and blood glucose in sera were remarkably lower in the Cordyceps militaris extract intake group than in the hyperlipidemic rats. In the ratio of HDL-cholesterol concentration was higher percentage in the Cordyceps militaris extract intake group than in the hyperlipidemic rats. The activities aminotransferase (AST, ALT) in sera were rather lower in the Cordyceps militaris extract administration than in the hyperlipidemic rats. From the above research, Cordyceps militaris extract were effective on the improvement of the lipid compositions in sera of dietary hyperlipidemic rats.
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KEYWORD
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Cordyceps militaris, Cholesterol, Lipid composition, Aminotransferase, Hyperlipidemia
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